RNA In Response To External Events
Memory transfer was a biological process proposed by James V. McConnell and others in the 1960s. Memory switch proposes a chemical basis for memory termed memory RNA which may be passed down via flesh as a substitute of an intact nervous system. RNA in response to external occasions, it'd also be utilized in neurons to record stimuli. This was proposed as an explanation for the outcomes of McConnell's experiments during which planarians retained memory of acquired info after regeneration. In McConnell's experiments, he classically conditioned planarians to contract their bodies upon exposure to gentle by pairing it with an electric shock. The planarians retained this acquired data after being sliced and regenerated, even after multiple slicings to produce a planarian where none of the unique trained planarian was present. The same held true after the planarians have been floor up and fed to untrained cannibalistic planarians, often Dugesia dorotocephala. Because the nervous system was fragmented but the nucleic acids weren't, this seemed to indicate the existence of memory RNA.
Memory switch by memory RNA shouldn't be currently a properly-accepted explanation for the planarian habits. Tan, Loh Teng-Hern; Ser, Hooi-Leng; Ong, Yong Sze; Khaw, Kooi Yeong; Pusparajah, Priyia; Chan, Kok-Gan; Lee, Learn-Han; Goh, Memory Wave Bey-Hing (2020). "Reckoning the Unresolved Scientific Question on Memory Transfer". Progress in Drug Discovery & Biomedical Science. Bob Kentridge. "Investigations of the cellular bases of memory". McFarling, STAT, Usha Lee. Dave, Shivani (2018-05-14). "'Memory Wave Protocol transplant' achieved in snails". William L. Mikulas. "Physiology of Learning". University of West Florida. McConnell, James (1965). "The trendy Search for the Engram" (PDF). In McConnell (ed.). A Handbook of Psychological Experimentation on Planarians. The Worm Runner's Digest. 5, Memory Wave 7. Archived from the unique (PDF) on 2012-04-18 - via Tufts University. Duhaime-Ross, Arielle (17 September 2013). "Flatworms Recall Acquainted Environs, Even after Dropping Their Heads". Shomrat T, Levin M (2013-07-02). "An automatic training paradigm reveals long-term memory in planaria and its persistence by head regeneration". The Journal of Experimental Biology. 216 (20): 3799-3810. doi:10.1242/jeb.087809. This biochemistry article is a stub. You will help Wikipedia by expanding it.
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